In order to have a cin 3 pap test result, do the cells have to go through cin 1and 2 first? MDs or RNs please?

I am not a doctor but I screen paps. The answer to your question is that CIN and LSIL, HSIL are used interchangeably. Doctors usually use the CIN description because they do biopsies while cytotechs use the low grade, high grade references because we are looking at cells and not tissues. CIN 1 refers to low grade, CIN 2 is usually moderate dysplasia (a step after cin 1 or low grade and for cytotechs is considered already high grade) and CIN 3 is severe dysplasia (high grade, which is a step above moderate). To answer your question, yes, it is possible to go through all stages CIN 1 to CIN 3, especially if you have high risk HPV. There is also the possibility of different areas of your cervix having different levels of CIN. When a doctor does a pap, sometimes not all surface areas of the cervix are sampled, so if there are any other sections where say CIN 3 was located, it may have been covered up by CIN 1 cells, or just next to it CIN 2 cells. So in essence this all depends on the sampling done by the doctor. LEEP goes a little deeper so there happened to be CIN 3 in the deeper layers. This progression from CIN 1-->3 can go very rapidly and also depends on what strain of HPV you have (high risk is especially virulent). Or it could have taken a while but was never sampled because of the depth it was in your cervix. If there were no signs of microinvasion and they got it all you should be fine. They will monitor you with repeat paps every 3-6 months for the first year, then the second year every 6 months. If all stays negative after that then you can go back to having paps once a year. Do not be alarmed....keep up with your paps and your doctor will take care of you.